For Pete’s sake, no! All screws are usually only slightly fastened so you’ll be able to loosen them with very little effort. There’s very little room for jiggling about inside the phone, so there’s no benefit to using excessive force on the poor screws. On the contrary, fastening them too tightly can damage your phone!
Usually a light touch is all they need to get loose. Use the same light twist of the wrist to fasten them again. This applies to the external, as well as the internal screws.